联系方式

电话:

传真:

邮箱:songwu@whu.edu.cn

个人主页


吴松     

学历:博士

现任职务:教授 


学习经历:

1989.09-1993.06   湖北大学化学系  本科   化学教育

2000.09-2005.12   9778818威尼斯化学院  博士   有机化学


工作经历:

1993.06-2000.05  湖北省沙市一中 高中教师

2005.12-2007.11  9778818威尼斯 讲师

2007.11-2023.11  9778818威尼斯 副教授

2023.11-至今    9778818威尼斯  教授

2009.5-2011.5   斯坦福大学医学院 博士后  抗肝癌药物的合成及肿瘤的早期检测(成像研究)


科研经历:

主持两项国家自然科学基金面上项目,并主持过多项校企联合项目。

科研方向:

1. 以疾病相关的生物标志物为靶标,设计并合成可与这些靶标特异性反应的荧光探针用于疾病的诊断。相关工作曾为美国化学学会(ACS)旗下的新闻周刊C&EN (Chemical & Engineering News)专题报道。

2. 由疾病相关生物标志物诱发的集疾病治疗与诊断为一体的荧光诊疗探针的研究。

代表性文章:

1. Wenxiang Wang, Tian Yang, Qinyong Zhang, Kang Lu, Zhonghui Zheng, Cuiqing Tian, Jie Ping, Baiwen Qi, and Song Wu*. Development of a Facile Lysosome-Targeting Nitric Oxide Fluorescent Probe Based on a Novel Reaction Mechanism. Analytical Chemistry, 2023, 95 (15), 6279-6286.

2. Kang Lu, Yu Wang, Hao Zhang, Cuiqing Tian, Wenxiang Wang, Tian Yang, Baiwen Qi, and Song Wu*. Rational Design of a Theranostic Agent Triggered by Endogenous Nitric Oxide in a Cellular Model of Alzheimer’s Disease. Journal of Medicinal Chemistry, 2022, 65, 9193-9205.Reported by X-MOL

3. Hengtang Mai, Yu Wang, Shuang Li, Ruizhen Jia, Sixian Li, Qian Peng, Yan Xie, Xiang Hu and Song Wu*. A pH-sensitive near-infrared fluorescent probe with alkaline pKa for chronic wound monitoring in diabetic mice. Chemical Communication, 2019, 55, 7374-7377.

4. Ruizhen Jia, Pengfei Song, Jingjing Wang, Hengtang Mai, Sixian Li, Yu Cheng, Song Wu*. Self-Assembled Fluorescent Nanoprobe Based on Forster Resonance Energy Transfer for Carbon Monoxide in Living Cells and Animals via Ligand Exchange. Analytical Chemistry, 2018, 90, 7117-7121.

5. Jin Chen, Lingyu Zeng, Tian Xia, Shuang Li, Tengfei Yan, Song Wu*, Guofu Qiu, Zhihong Liu*. Toward a Biomarker of Oxidative Stress: A Fluorescent Probe forExogenous and Endogenous Malondialdehyde in Living Cells. Analytical Chemistry, 2015, 87, 8052~8056. (Reported by C&EN)

6. Tengfei Yan, Jin Chen, Song Wu*, Zhiqiang Mao, Zhihong Liu*. A rationally designed fluorescence chemosensor for on-site monitoring of carbon monoxide in air. Organic Letters2014,16:3296-3299.

7. Song Wu, Qizhen Cao, Xiaolin Wang, Kai Cheng, Zhen Cheng*. Design, synthesis and biological evaluation of mitochondria targeting theranostic agents. Chemical Communication, 2014, 50: 8919~8922.