报告题目：Unleashing the power of nature - A synthetic biology approach

报告人：张数一 博士

工作单位：麻省理工学院

报告时间：2019年6月3日（星期一）10:30

报告地点：9778818威尼斯医学部8号楼9楼会议室

报告摘要：Synthetic biologists have engineered microbes to produce a wide range of biomaterials and biofuels, which are usually derived from major metabolites of the central metabolic pathways inside cells. We recently identified a new branch of TCA cycle, which enables metabolic engineering strategies to improve yields of poly-3-HB and poly-3-HB-co-4-HB in cyanobacteria. In addition, understanding and harnessing the capability to built regulatory networks and control gene expression levels under different growth conditions will offer potential solutions to both biotechnological and biomedical challenges. To this end, we engineered a non-toxic variant of dCas9 and explored its application in genetic circuit construction and synthetic biology.

报告人简介：

张数一，现于麻省理工学院进行博士后研究。2009年本科毕业于清华大学，2015年在宾夕法尼亚州立大学取得博士学位。主要研究方向为合成生物学、光合作用、代谢工程等。已经在Science, Metabolic Engineering, Nucleic Acids Research等期刊发表论文14篇，被引用500余次。