Subjects: Pharmaceutics

Department: School of Pharmaceutical Sciences

Title: Professor

Email: weili.mn@whu.edu.cn

Address: NO.185 Donghu Road, Wuchang District, Wuhan, 430071, China

Education：

2005.09 - 2009.06  Huazhong University of Science and Technology，Bachelor

2009.09 - 2012.03  Huazhong University of Science and Technology，Master

2012.09 - 2015.10  City University of Hong Kong，Ph.D.

Working Experience：

2016.02-2020.09  Georgia Institute of Technology，Postdoc

2020.10-now  Wuhan University, Professor

Teaching：

Pharmaceutics

Research interests：

Microneedles; Drug delivery; Transdermal drug delivery; Sustained release

Publications：

1. W. Li, Jie Tang, Dennis Lee, Thomas Tice, Steven Schwendeman, and Mark Prausnitz*, “Clinical Translation of Long-acting Drug Delivery Formulations” Nature Reviews Materials (2022)

2. W. Li, R. Terry, J. Tang, M. Feng, S. Schwendeman, M. Prausnitz*, “Rapidly Separable Microneedle Patch for the Sustained Release of a Contraceptive” Nature Biomedical Engineering, 3: 220 229 (2019) (Highlighted by Nature Biomedical Engineering, Nature Reviews Materials, Science Daily and homepage of Georgia Institute of Technology)

3. W. Li, J. Tang, R. Terry, S. Li, A. Brunie, R. Callahan, R. Noel, C. Rodriguez, S. Schwendeman, M. Prausnitz*, “Long-acting Reversible Contraception by Effervescent Microneedle Patch”, Science Advances, 5 (11), eaaw8145 (2019) (Featured by Science and highlighted by homepage of Georgia Institute of Technology).

4. W. Li#*, S Li#, X Fan, MR Prausnitz*, “Microneedle patch designs to increase dose administered to human subjects”, Journal of Controlled Release (2021)

5. W. Li*, J. Chen, R. Terry, J. Tang, A. Romanyuk, S. Schwendeman, M. Prausnitz*,“Core-shell microneedle patch for six-month controlled-release contraceptive delivery”, Journal of Controlled Release (2022) DOI: 10.1016/j.jconrel.2022.04.051

6. X. Jiang, H. Zhao, W. Li*, “Microneedle-mediated Transdermal Delivery of Drug-carrying Nanoparticles”, Frontiers in Bioengineering and Biotechnology, 10, 840395 (2022)

7. C. Wang, X. Jiang, Y. Zeng, R. Terry, W. Li*, “Rapidly separable microneedle patches for controlled release of therapeutics for long-acting therapies”, Medicine in Drug Discovery, 13, 100118 (2022)

8. W. Li#, R. Luo#, A. D. jadhav, Z. Zhang, X. Lin, L. Yan, X. Chen, J. He, C.H. Chen, P. Shi*, “Remote Modulation of Neural Activities via Near infrared Triggered Release of Biomolecules”, Biomaterials, 65: 76 85 (2015)

9. W. Li, Z. Xu, B. Xu, C.Y. Chan, X. Lin, Y. Wang, G. Chen, Z. Wang, Q. Yuan, G. Zhu, H. Sun, W. Wu, P. Shi*, “Investigation of the Subcellular Neuro-toxicity of β-Amyloid Using a Device Integrating Microfluidic Perfusion and Chemotactic Guidance”, Advanced Healthcare Materials, 6: 7 (2017)

10. W. Li, J. Lin, T Wang, P. Huang*, “Photo triggered Drug Delivery Systems for Neuron related Applications”, Current Medicinal Chemistry, 26: 1406 1422 (2019)

11. W. Li, Q. Tang, A.D. Jadhav, A. Narang, W. Qian, P. Shi*, and S.W. Pang*. “Large scale Topographical Screen for Investigation of Physical Neural Guidance Cues”, Scientific Reports, 5: 8644 (2015)

12. W. Li#, Z. Xu#, X. Lin, R. Luo, C. Chen, P. Shi*, “NeuroArray: A Universal Interface for Patterning and Interrogating Neural Circuitry with Single Cell Resolution”, Scientific Reports, 4:4784 (2014)

13. M. Prausnitz*, Y. Gomaa, W. Li, “Microneedle Patch Drug Delivery in The Gut”, Nature Medicine, 25, 1471--1472 (2019)

14. Y. Lee, W. Li, J. Tang, S. Schwendeman, M. Prausnitz “Immediate detachment of microneedles by interfacial fracture for sustained delivery of a contraceptive hormone in the skin”, Journal of Controlled Release, 337:676-685 (2021)

15. C. Wu, P. Jiang, W. Li, H. Guo, J. Wang, J. Chen, M. Prausnitz, Z. Wang*, “Self--powered Iontophoretic Transdermal Drug Delivery System Driven and Regulated by Biomechanical Motions” Advanced Functional Materials. (2019)

16. B. Xu, X. Lin, W. Li, Z. Wang, W. Zhang, P. Shi*, “Cell Generator: A Self--Sustaining Biohybrid System Based on Energy Harvesting from Engineered Cardiac Microtissues”, Advanced Functional Materials, 27: 1606169 (2017)

17. Y. Wang, Y. Yang, L. Yan, S. Y. Kwok, W. Li, Z. Wang, X. Zhu, G. Zhu, W. Zhang, X. Chen and P. Shi*, “Poking Cells for Efficient Vector--free Intracellular Delivery”, Nature Communications, 5: 4466 (2014)

18. R. Luo, Z.H. Lim, W. Li, P. Shi, C.H. Chen*. “Near--infrared Light Triggerable Deformation--free Polysaccharide Double Network Hydrogels”, Chemical Communication, 50, 7052--7055 (2014)

19. S. Li, W. Li, M. Prausnitz*, “Individually coated microneedles for co--delivery of multiple compounds with different properties”, Drug Delivery and Translational Research, 8: 1043--52 (2018)

20. A.D. Jadhav, Y. Bao, R. Luo, W. Li, Z. Xu, C.H. Chen, P. Shi*, “Photoresponsive Microvalve for Remote Actuation and Flow Control in Microfluidic Devices”, Biomicrofluidics 9, 034114 (2015)

21. A.D. Jadhav, W. Li, P. Shi*. “Compartmentalized Platforms for Neuro--pharmacological Research”, Current Neuropharmacology, 14: 72 (2016)